But, after all, should my object in endeavouring to convince the more enlightened parts of the community, (from whom alone I can hope for a proper consideration of the evidence I have adduced,) be attained, much will yet remain to be done: and I have endeavoured to point out the necessity of a general co-operation, in order to give the fullest effect to the paramount capabilities of Vaccination.—Amongst the poorest and least informed classes of society, a written evidence of this description, can scarcely be expected either to gain access or to meet with the requisite consideration; and the ignorance, the prejudices, and the _apathy_, which have been found to exist in some of them, must therefore be overcome by other means. It is my wish to direct attention more especially to the _latter_ difficulty, having myself witnessed some instances, and having been informed of many others, wherein the parents have regarded the health and lives of their children so little, as not only to despise the security afforded by Vaccination, but to omit the most ordinary precautions against Small Pox infection, and to reject the gratuitous medical assistance which was within their reach.[1] ----- Footnote 1: Mr. Wilkie (the respectable resident apothecary at the Dispensary in this town) lately informed me that a woman, who resides in Sandgate, after losing _three children_ from Small Pox, during the present prevalence of that disease, would yet neither use precautions nor remedial measures for the preservation of the remainder; although she daily witnessed the efficacy of Vaccination among her neighbours, even when performed during the existence of Small Pox itself in other members of the same families. ----- But there are links by which all the various classes of society, from the highest to the lowest, are connected; and it is through the medium of these that we must hope for the removal of the difficulties referred to. There are few of the rich, who have not the power of influencing some of the poor, nor do I believe there are any of the latter who may not be influenced by some one or other of the former. Whether this influence may be exerted through interest, through persuasion, or through the conviction of reason, is a matter of less moment than the attainment of the end in view—namely, _to induce all, without exception, to have their children vaccinated during infancy_—and were it employed in its fullest extent, this end might certainly be accomplished.