The following is extracted from the London Medical and Physical Journal for the present month (December):—“_Influence of Vaccination upon the mortality of Berlin._ M. Casper has published a long paper, containing many curious details relative to the above subject; but we can do no more, at present, than give the result of his investigations. 1. The Small Pox formerly carried off from the 12th to the 10th of the population. 2. Formerly, at Berlin, one out of twelve children born, died of the Small Pox; now the deaths from the same cause are 1 in 116.”—_Journal Comp. September._ In London, as has been already shown, the number of deaths from Small Pox has been diminished from 1 in 10 to 1 in 28. It is obvious, therefore, that, were Vaccination employed in the latter city to the same proportional extent as at Berlin, a further saving of more than 500 lives annually would be effected, within the bills of mortality. ----- 2. That in accomplishing this result, Vaccination has acted in two ways,—1. by superseding the practice of inoculation for Small Pox, which (while it afforded a certain degree of security to the inoculated) has been proved to have materially increased the gross number of deaths, by creating, artificially, many new sources of infection,—and, 2. by rendering the vaccinated entirely insusceptible of Small Pox infection, or the disease produced by it, in almost every instance, mild, harmless, and devoid of danger. 3. That Vaccination is capable, if universally employed, of exterminating the Small Pox altogether, as has been proved by the experience of other countries. That Vaccination is a process perfectly unattended with danger to the individual who passes through it, and incapable of communicating any noxious infection to those around him, are facts too well known and too generally admitted, to require more than a passing notice; nevertheless it is essential that they should not be lost sight of.