An ethical problem; or, Sidelights upon scientific experimentation on man and animalsLeffingwell, Albert
Philosophy
An ethical problem; or, Sidelights upon scientific experimentation on man and animals
Leffingwell, Albert
Medicine, Experimental; Vivisection
EXPREIMENT 76. Dog. Among other procedures, the vivisectors "APPLIED
A LARGE GAS-FLAME to the posterior extremities in the region of the
knee; a slight rise. Repeated the application for a longer time;
slight rise.... APPLICATION OF A BUNSEN FLAME TO THE NOSE, PRODUCING A
SLIGHT RISE IN BLOOD-PRESSURE."
EXPERIMENT 82. A small female dog; weight oly 9 pounds. Time of
experiment, one hour and fifty-five minutes. "One-third of a grain of
CURARE and one-twelfth of a grain of morphia were injected into the
jugular vein." After various manipulations, there was "APPLICATION OF
BUNSEN'S FLAME TO THE RIGHT HIND-FOOT," causing "AN APPRECIABLE RISE
IN THE BLOOD-PRESSURE."
EXPERIMENT 87. Dog. Time of experiment, two hours and forty-five
minutes. "Injected CURARE and morphine into the jugular vein;
artificial respiration maintained.... The sciatic nerve was exposed
and stimulated by a faradic current. A SHARP INCREASE IN
BLOOD-PRESSURE during the period of stimulation was noted."[1]
[1] Concerning the rise of blood-pressure as the sign of an animal's
sensibility to painful impressions, when under the influence of
CURARE, see testimony of Professor Gotch of Oxford University, quoted
on a preceding page.
EXPERIMENT 94. "Electrical stimulation of sciatic nerve produced
MARKED INCREASE IN BLOOD-PRESSURE.... Application of Bunsen's flame to
the foot; RISE IN BLOOD-PRESSURE.... REPEATED APPLICATION OF BUNSEN'S
FLAME FOR A PERIOD OF TWO MINUTES PRODUCED DECIDED RISE IN BLOOD-
PRESSURE."
EXPERIMENT 95. "Application of Bunsen's flame to the paw produced but
slight rise.... Bunsen's flame applied to the foot, CAUSING RISE IN
BOTH PRESSURES.... Application of BUNSEN'S FLAME NOW PRODUCED A SHARP
RISE IN THE PRESSURES." Then the blood-pressure fell, and though the
vivisector applied flame to the intestines, it produced no effect so
far as the blood-pressure was concerned.
EXPERIMENT 97. "Application of A BUNSEN'S FLAME PRODUCED THE
CHARACTERISTIC INCREASE IN BLOOD-PRESSURE.... Stimulation of the
sciatic nerve by the faradic current produced an INCREASE IN BLOOD-
PRESSURE.... Repetition of the stimulus produced A FURTHER RISE IN
BLOOD-PRESSURE...."
EXPERIMENT 110. "Application of Bunsen's flame PRODUCED A SHARP
RISE...."
EXPERIMENT 113. "Bunsen's flame applied to the posterior and anterior
extremities PRODUCED A MARKED RISE IN PRESSURE.... BUNSEN'S FLAME OVER
REGION OF THE HEART PRODUCED A GRADUAL RISE."
EXPERIMENT 131. "Bunsen's flame to the right hind-foot was followed by
A RATHER MARKED RISE IN CENTRAL BLOOD-PRESSURE."
EXPERIMENT 132. "BUNSEN'S FLAME TO THE NOSE CAUSED A GENERAL RISE IN
BLOOD-PRESSURE."
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