The Medical Times and Gazette of London was one of the earlier of medical journals to denounce the cruelties perpetrated by vivisection abroad. In its issue of September 4, 1858, the editor says: "In this country we are glad to think that experiments on animals are never performed nowadays except upon some reasonable excuse for the pain thus wilfully inflicted. We are inclined to believe that the question will some day be asked, whether any excuse can make them justifiable? One cannot read without shuddering details like the following. It would appear from these that the practice of such brutality is the everyday lesson taught in the veterinary schools of France. "A small cow, very thin, and which had undergone numerous operations-- that is to say, WHICH HAD SUFFERED DURING THE DAY THE MOST EXTREME TORTURE--was placed upon the table, and killed by insufflation of air into the jugular vein."[1] This fact is related by M. Sanson, of the veterinary school of Toulouse, merely incidentally, when describing an experiment of his own upon the blood. The wretched animal was actually cut to pieces by the students! ... M. Sanson adds (merely wanting to prove that the nervous system of the animals upon which he operated was properly stirred up): `Those who have seen these wretched animals on their bed of suffering--lit de douleur--know the degree of torture to which they are subjected; torture, in fact, under which they for the most part succumb!'" [1] In all extracts italics are the compiler's. A little later the same medical journal again touched the subject of vivisection in its editorial columns. In its issue of October 20, 1860, the editor is even more emphatic in denunciation: "Two years ago we called attention to the brutality practised at the veterinary schools in France, and gave a specimen of the kind of torture there inflicted upon animals. WE ARE VERY GLAD TO SEE THAT THE PUBLIC ARE NOW OCCUPIED WITH THE SUBJECT, and we are sure that the Profession at large will fully agree with us IN CONDEMNING EXPERIMENTS WHICH ARE MADE SIMPLY TO DEMONSTRATE PHYSIOLOGICAL OR OTHER FACTS WHICH HAVE BEEN RECEIVED AS SETTLED POINTS AND ARE BEYOND CONTROVERSY. We consider the question involved as one of extreme interest to the Profession, and we shall gladly throw open our columns to any of our brethren who may wish to assist in framing some code by which we may decide under what circumstances experiments upon living animals may be made with propriety."