An Introduction to the History of ScienceLibby, Walter
History
An Introduction to the History of Science
Libby, Walter
Science -- History
His own study of racemic acid, begun in the laboratories of Paris, and
followed up in the factories of Leipzig, Prag, and Vienna, had led to
his theory of molecular dissymmetry, the starting point of modern
stereo-chemistry. It now gave rise on Pasteur's part to new studies and
to new applications to the industries. He tried an experiment which
seems almost whimsical, placing ammonium racemate in the ordinary
conditions of fermentation, and observed that only one part--the
dextro-rotatory--ferments or putrefies. Why? "Because the ferments of
that fermentation feed more easily on the right hand than on the left
hand molecules." He succeeded in keeping alive one of the commonest
moulds on the surface of ashes and racemic acid, and saw the
lævo-tartaric acid appear. It was thus that he passed from the study of
crystals to the study of ferments.
In the middle of the nineteenth century little was known of the nature
of fermentation, though some sought to explain by this ill-understood
process the origin of various diseases and of putrefaction. Why does
fruit-juice produce alcohol, wine turn to vinegar, milk become sour, and
butter rancid? Pasteur's interest in these problems of fermentation was
stimulated by one of the industries of Lille. He was accustomed to visit
with his students the factories of that place as well as those of
neighboring French and Belgian cities. The father of one of his students
was engaged in the manufacture of alcohol from beetroot sugar,
and Pasteur came to be consulted when difficulties arose in the
manufacturing process. He discovered a relationship between the
development of the yeast and the success or failure of the fermentation,
the yeast globules as seen under the microscope showing an alteration of
form when the fermentation was not proceeding satisfactorily. In 1857
Pasteur on the basis of this study was able to demonstrate that
alcoholic fermentation, that is, the conversion of sugar into alcohol,
carbonic acid, and other compounds, depends on the action of yeast, the
cells of which are widely disseminated in the atmosphere.
Public-domain text, read in full here on John Shaqi.
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