In autumn it is not uncommon to see flies motionless upon a window-pane, with a sort of magic circle, in white, drawn round them. On microscopic examination, the magic circle is found to consist of innumerable spores, which have been thrown off in all directions by a minute fungus called _Empusa museæ_ the spore-forming filaments of which stand out like a pile of velvet from the body of the fly. These spore-forming filaments are connected with others which fill the interior of the fly's body like so much fine wool, having eaten away and destroyed the creature's viscera. This is the full-grown condition of the _Empusa_. If traced back to its earliest stages, in flies which are still active, and to all appearance healthy, it is found to exist in the form of minute corpuscles which float in the blood of the fly. These multiply and lengthen into filaments, at the expense of the fly's substance; and when they have at last killed the patient, they grow out of its body and give off spores. Healthy flies shut up with diseased ones catch this mortal disease, and perish like the others. A most competent observer, M. Cohn, who studied the development of the _Empusa_ very carefully, was utterly unable to discover in what manner the smallest germs of the _Empusa_ got into the fly. The spores could not be made to give rise to such germs by cultivation; nor were such germs discoverable in the air, or in the food of the fly. It looked exceedingly like a case of Abiogenesis, or, at any rate, of Xenogenesis; and it is only quite recently that the real course of events has been made out. It has been ascertained that when one of the spores falls upon the body of a fly, it begins to germinate, and sends out a process which bores its way through the fly's skin; this, having reached the interior cavities of its body, gives off the minute floating corpuscles which are the earliest stage of the _Empusa_. The disease is "contagious", because a healthy fly coming in contact with a diseased one, from which the spore-bearing filaments protrude, is pretty sure to carry off a spore or two. It is "infectious" because the spores become scattered about all sorts of matter m the neighbourhood of the slain flies. Silkworms are liable to many diseases; and, even before 1853, a peculiar epizootic, frequently accompanied by the appearance of dark spots upon the skin (whence the name of "Pébrine" which it has received), had been noted for its mortality. But in the years following 1853 this malady broke out with such extreme violence, that, in 1858, the silk-crop was reduced to a third of the amount which it had reached in 1853; and, up till within the last year or two, it has never attained half the yield of 1853. This means not only that the great number of people engaged in silk growing are some thirty millions sterling poorer than they might have been; it means not only that high prices have had to be paid for imported silkworm eggs, and that, after investing his