Considering the paucity of our observations bearing upon this important point, it seems impracticable to make any positive statements with reference to the assistance that we might possibly derive from the use of Apis in this disease. My own opportunities for observation having been very few, I recommend the use of Apis in white swelling of the knee, to my professional brethren. The following symptoms in "Hering's American Provings," seem to indicate it; No.'s 828, 829 and 931, "violent pain in the left knee, externally, above and below the knee, particularly above, somewhat in front; painful œdematous swelling of the knee; burning stinging about the knee." In white swelling of the knee, where no allœopathic treatment has yet been pursued, I recommend Iodine 30, one globule, in six dessert-spoonfuls of water, a dessert-spoonful morning and evening, until the whole is finished; after this wait three days, and then give Apis 3, as before mentioned, a tablespoonful every hour or three hours, or a drop morning and evening, according as the pain or danger is more or less pressing. Apis is more especially useful in removing pain, in changing the secretion of ichor to that of healthy pus, and in arresting the consumptive fever. After these results have been accomplished, we permit the previously given Iodine to achieve the cure. If Iodine had been abused under allœopathic treatment, before the homœopathic treatment commenced, we give Iodine 5000, one globule, in order to subdue the Iodine diathesis, and thus remove the most powerful obstacle to a cure. Any one who knows more about this point, will please mention it. Although Apis acts well in white swelling of the knee, which is comparatively a rare disease, yet it is far more useful in DYSENTERY.