The temperature of animals in a state of health is not a fixed quantity, but has a limited range which depends upon internal and external conditions not incompatible with health. In man the range of temperature in health is fixed at 97.25° F. to 99.5° F. Any temperature above or below these extremes, unless explained by special circumstances not affecting the normal condition of the person, is an indication of disease. This comparatively fixed temperature in health is a remarkable feature of the living animal. When subjected to a temperature above or below the extremes here given it will still maintain its equilibrium. This fixed temperature under varying conditions of heat and cold is due to a "heat-regulating power," inherent in the constitution of every animal, by which it imparts heat when the temperature of the air is high and conserves heat when the latter is low. The heat escapes from the body--1, by radiation from the surface; 2, by transmission to other bodies; 3, by evaporation; and 4, by the conversion of heat into motion. The surface of the body furnishes the principal medium for the loss of heat by the first three methods--viz., radiation, transmission, and evaporation. It is estimated that 93.07 per cent of the heat produced escapes by the processes of radiation, evaporation, conduction, and mechanical work. The remaining heat units are lost by warming inspired air and the foods and drinks taken. There are apparently other subtile influences, so-called "regulators of heat," at work to preserve an equilibrium of temperature in the animal body, but they are not well known. The result of the operation of these forces is this--viz., if, by any means, the heat of the body is increased, compensative losses of heat quickly occur, and the normal temperature is soon restored; and if, on the contrary, the loss of heat is unusually increased, the compensative production of heat of the body at once follows, and the equilibrium is at once restored. The important fact to remember is this--viz., the production and loss of heat in the human organism when in health and not subjected to too violent disturbing causes are so nicely balanced that the temperature is always maintained at an average of 98.6° F., the extremes being 97.25° F. and 99.5° F. "So beautifully is this balance preserved," Parkes remarks, "that the stability of the animal temperature in all countries has always been a subject of marvel." If, however, anything prevents the operation of the processes of cooling--viz., radiation, evaporation, and conduction--the bodily temperature rises by the accumulation of heat, and death is the result from combustion. In experiments in ovens a man has been able to bear a temperature of 260° F. for a short period, provided the air was dry so that evaporation could be carried on rapidly. But if the air is very moist, and perspiration is impeded, the temperature of the body rises rapidly, and the person soon succumbs to the excessive heat.