In all we have kept constantly in view the pathology of the disease, whose "dictates" have governed us in the exhibition and establishment of a general principle of rational practice, confirmed by observation and experience, which, if accepted and carried out by the profession, we hope and trust will save a very large proportion of those attacked by "this most acute of acute diseases." AUTHORS. CONTENTS. CHAPTER I. SEC. I. ORIGIN AND DEVELOPMENT. 7 SEC. II. PROGRESS AND FATALITY. 20 SEC. III. CAUSES--PROPAGATION. 34 CHAPTER II. SEC. I. PATHOLOGY. 45 SEC. II. PHENOMENA, OR SYMPTOMS. 55 CHAPTER III. SEC. I. UNSUCCESSFUL MODES OF TREATMENT.--VENOUS TRANSFUSION EXPLAINED. 64 SEC. II. PHYSIOLOGICAL CONDITION OF THE BLOOD, ITS NON-AERATION, OR NON-OXYDATION. MAXIMS OF RATIONAL PRACTICE SUGGESTED. 91 SEC. III. DIFFERENT MODES OF TREATMENT. 130 SEC. IV. STATISTICS. PERCENTAGE OF LOSS. VARIABLE RESULTS--THEIR CAUSE. 166 CHAPTER IV. SEC. I. GENERAL PRINCIPLE OF RATIONAL PRACTICE, DICTATED BY THE PATHOLOGY OF THE DISEASE, CONFIRMED BY OBSERVATION AND EXPERIENCE. 178 SEC. II. REMEDIES, RECIPES, ETC. 188 SEC. III. PROPHYLAXIS, OR MEANS OF PREVENTION. 203 SEC. IV. FORMULÆ--PREPARATIONS, ETC. 213 ASIATIC CHOLERA. CHAPTER I. SECTION I.--ORIGIN AND DEVELOPMENT. Epidemics have occasionally prevailed in all ages. Sometimes they have been circumscribed in their influence, and limited to particular localities; while at other periods they have taken a wider range and extended over larger sections, inflicting the most lamentable results, and augmenting the bills of mortality to an incredible degree.