A student who will have reached age 21 on or before May 1, preceding the ISF is not eligible to participate as a finalist in the ISF. I A student may enter only one project and it must be his own work. Group projects involving two or more students give experience to beginners and are acceptable in S or R fairs but may not be entered in the ISF. I The identical repetition of previous year’s project is not permitted. However, a student may again exhibit work on a continuing problem provided the work demonstrates considerable progress when compared with the previous year. I Finalists must be accompanied to the ISF by an official adult escort designated and/or sponsored by the regional fair. Responsibility and liability for entry in the ISF rests with the affiliated fair organization which finances the entry, provides transportation for the finalists and their projects, and living expenses during ISF. I Students planning to enter exhibits in the ISF which contain materials that may be regulated by a quarantine should first consult with a Federal or State plant pest control or animal health inspector, a county agricultural agent, or write to the Director, Plant Pest Control Division, U. S. Department of Agriculture, Federal Center Building, Hyattsville, Maryland 20782. S-R-I Regulations for Experiments With Animals _This guide was prepared and approved by the National Society for Medical Research, the Institute of Laboratory Animal Resources (National Research Council), and the American Association for Laboratory Animal Science (1968)._ 1. The basic aims of scientific studies involving animals are to achieve an understanding of life and to advance our knowledge of life processes. Such studies lead to respect for life. 2. Insects, other invertebrates and protozoa are materials of choice for many experiments. They offer opportunities for exploration of biological principles and extension of established ones. Their wide variety and the feasibility of using larger numbers than is usually possible with vertebrates makes them especially suitable for illustrating principles. 3. A qualified adult supervisor must assume primary responsibility for the purposes and conditions of any experiment that involves living animals. 4. No experiment should be undertaken that involves anesthetic drugs, surgical procedures, pathogenic organisms, toxicological products, carcinogens, or ionizing radiation unless a trained life scientist, physician, dentist or veterinarian directly supervises the experiment. 5. Any experiment must be performed with the animal under appropriate anesthesia if pain is involved.