The patient staggers as he walks, and soon, unless relief comes, he will become totally paralyzed. Spots of blood appear just beneath the skin and especially upon the limb bitten. If the amount of the virus is sufficient to produce death, all the above symptoms are soon followed by tetanic convulsions and lockjaw. If, however, the dose is not sufficient to produce death, they gradually subside, leaving the patient much debilitated and subject to poisoned blood states that manifest themselves in the form of skin eruptions and ulcers. The reader will appreciate that in the above has been pictured an extreme case. Nothing like nearly all cases bitten present even half the symptoms described. Statistics reveal that only something like 12 per cent. of all persons bitten by the New World venomous serpents die from their wounds. Before passing to a consideration of the means for combating a poison let us pause for a time and glance at the probabilities of being struck even in a country where venomous serpents abound. The "rim rock" of the Columbia River in Washington and Oregon is an ideal place for rattlesnakes and they abound there in profusion. Children run barefoot all summer among the basaltic rocks, and but few of them are bitten. Haymakers fork them up with the haycocks, harvesters find them beneath the bundles of bound grain, still it is rare to hear of an accident. Among the "brakes" of the Clearwater in Idaho the great "timber" rattler dwells. The Indians never molest him, yet during my nine years' sojourn among them only seven cases appeared, and two of these were very young children. Still, people are bitten, and the location of the wound has much to do with the chances of recovery. About 60 per cent. of all persons wounded are struck on the lower limbs, thirty-five on the hand or arm, and five on the trunk and face. Of these, wounds on the lower limbs are the least dangerous and those on the trunk or face, being near large nerve and arterial vessels, most so. The more remote from the general circulation, the less danger from the wound. The treatment of a rattlesnake wound resolves itself into the application of a few very simple rules. In the first place a person wounded by a snake usually does the very thing he should not do—that is, goes tearing off at top speed for the nearest human habitation, thereby increasing the circulation and disseminating the virus through the system more rapidly. The man should sit calmly down and bind his handkerchief around the limb (if it is a limb), break off a stout twig and insert beneath the handkerchief, producing a rude tourniquet, and twist until the circulation is effectually shut off.