Chemical antidotes directed against the venom of serpents are extremely problematical. It is questionable if there is at present any chemical that will exert more than an antiseptic effect upon the virus. Permanganate of potassium may possess the property of setting up a chemical reaction, but if so it is so prone to deteriorate when in solution and requires so much time to place in solution that it is nearly valueless. Ammonia applied to certain of the less dangerous venoms is efficacious. Applied to crotalus poison it is of no use. In fact, when the matter is reduced to its lowest terms, the whole process of combating the effect of serpent venoms is comprised in what has been stated above. Restrict the circulation, destroy the virus by heat either chemically or by fire, and keep up the vital forces. Very few Indian tribes have any suggestion of a remedy for rattlesnake poison. The Moquis probably have, though if so no white man has ever been able to extract the secret from them. It is known that during the Moqui Snake Dance many Indians are bitten and none of them die. It might be inferred then that they do possess an effective antidote. In conclusion permit me to suggest an equipment for the treatment of rattlesnake wounds and briefly outline its uses. Procure a rubber ribbon about four feet long, technically known as an Esmarch tourniquet—this ribbon can be rolled into a compact form and is very elastic—; a sharp surgeon's knife known as a bistoury which should be securely wrapped in absorbent cotton; a blue bottle, or one about which several thicknesses of blue paper have been wrapped, containing a stick of silver nitrate; another bottle containing one hundred tablets of strychnia sulphate gr. 1/30; an all-metal hypodermic syringe for administering the same. All these should be placed in an oiled silk bag and kept in a convenient pocket. The bag should be changed when the clothing is changed just the same as the watch or compass. Now for their use: Let us suppose that you have encountered a rattler and are not too scared to know what you are doing. You quietly sit down, expose the limb, locate the wound, get out your Esmarch and beginning at one end wrap it securely about the limb _above_ the wound, gradually increasing the tension until the rubber sinks into the skin. This done, take your knife and make a deep X over the wound, using the cotton in which the knife was wrapped to sponge away the blood. Encourage free bleeding. If you are near a stream bathe the wound freely, either squeezing or sucking it. You need not fear to swallow the poison. It will do no harm in the stomach. After the wound has bled freely, take the stick of silver nitrate and burn it out quite to the bottom. All of this will hurt, of course, but it is necessary.