Prominent among the therapeutic advances of the century is the direct reduction of the high temperature of sunstroke and certain fevers by the use of cold. Although foreshadowed by Currie early in the century by his use of cold affusion in the treatment of scarlet fever, it did not come into general use until the closing decades. It is employed principally in typhoid fever, on the theory that a condition of high fever is in itself a source of danger quite distinct from the other injurious effects of a febrile disease. On the other hand, the employment of high degrees of heat has of late been shown to be a potent agency in the treatment of certain forms of disease, notably in various affections classed as rheumatic. Applications of very hot air, provided it is thoroughly dry, are borne without serious discomfort, and their employment promises to be of greater service in the conditions in which it is resorted to than that of any other agent. A revelation in the treatment of heart disease has been effected by the Bad Nauheim system of effervescent baths and resisted exercises. It is not only functional disorders of the heart that are relieved, but grave organic diseases also. Somewhat elaborate explanations of the way in which the treatment proves beneficial have been given, but they are not altogether satisfactory. Thus far we have dealt chiefly with those developments of medicine that seem to have been the outgrowth of much thought and experiment, but there was one that can hardly be viewed as other than a happy discovery, yet it was one that was fraught with unspeakable mitigation of human suffering, and that wrought a boundless extension of the field of surgery. It was that of anaesthesia. The first to discover an efficient surgical anaesthetic was Crawford W. Long, of Georgia. It has been established that he performed several minor operations with the patient anaesthetized with sulphuric ether, but he did not proclaim his discovery, and so it was reserved for William T. G. Morton, of Boston (then a dentist, but subsequently a physician), to make the first public demonstration of the efficiency of ether as an anaesthetic, which he did in the operating theatre of the Massachusetts General Hospital, in Boston, in the year 1846. The news of Morton's achievement spread broadcast, and it was at once realized that it was destined to revolutionize surgery. It certainly has done that, and in no less degree than was afterward accomplished by Listerism. Ether did not long remain the only anaesthetic known; Simpson, of Edinburgh, soon discovered that chloroform was possessed of even more decided anaesthetic properties. The inhalation of ether is disagreeable, and it is slow in producing the desired effect, whereas that of chloroform is not unpleasant, and it acts more rapidly. Consequently chloroform soon came to be generally preferred; but abundant experience has finally shown that ether is much the safer agent of the two, and improved