methods of administration have almost entirely done away with the objections to its use, so that now it is looked upon as the preferable general anaesthetic. But general anaesthesia--meaning the suspension of sensibility in the whole organism, including unconsciousness--is not always necessary, and sometimes it is undesirable. We have now trustworthy local anaesthetics, the chief of which is cocaine, wherewith we are able to anaesthetize the part to be operated on without rendering the patient unconscious, and the co-operation that a conscious patient may be able to render is sometimes valuable. It was not alone in the direct saving of human suffering that anaesthetics proved a boon to the world; they have made possible an amount of experimental work on animals in the way of vivisection that humane investigators would otherwise have shrunk from, necessary as it has been and still is for the advancement of the healing art. The operation of ovariotomy, first performed by Ephraim McDowell, of Kentucky, can hardly be classed with the happy accidents; but so little had been said about it or thought concerning it that when the news of it reached Europe "from the wilds of America" the editor of a ponderous English quarterly journal of medicine recorded his incredulity in the words "_Credat Judoeus, non ego_" An ovarian tumor inevitably proves fatal in the long run if it is not removed. In a certain percentage of cases it is malignant and will kill whether it is removed or not, but the general result of ovariotomy has been the saving of thousands of women from untimely death. Bell, of Edinburgh, had imagined the operation and had mentioned it in his lectures, but none the less to McDowell is due the credit of demonstrating its feasibility. Medicine bore quite its full share in the mitigation of the horrors and hardships of war that marked the Nineteenth Century. Its work was shown in the great reduction of pestilential disease incident to camp life, in prompt aid to the wounded, in the establishment of salubrious field and general hospitals, and in improved methods of transportation of the sick and wounded. Certainly the soldier on the sick list never before had such a fair prospect of rejoining his comrades safe and sound as he has now.