Bonaventure and Abraham died in the same year, 1652, but their sons, John and Daniel, were already of sufficient age and of sufficient training to assume the direction of affairs. Among the earlier of the works issued by these two, were an edition of the _Imitation of Christ_ and one of the _Psalms_, which are described by the enthusiastic Willems as “jewels of typography.” In 1655, Daniel transferred himself to Amsterdam, where he was associated with his cousin Louis. John’s death came a year or two later, leaving in Leyden no member of the Elzevir family. John’s widow, Eva van Alphen, thereupon made herself the head of the printing and publishing concern, and was able also to retain control of the business of the University. The activity of the publishing lessened during the following few years, but the excellence of the work turned out by the printing-office seems not materially to have suffered, and a number of the more important publications issued with the imprint of the Elzevir firm in Amsterdam, were manufactured in the Press of the Elzevir widow in Leyden. After the death of Eva, in 1681, there was, however, a rapid deterioration not only in the activity of the publishing, but in the work turned out by the printing-office. Her son Abraham appears to have been both ignorant and incapable. His business was before long limited to the printing of the University theses, and there were at the time not a few complaints from the instructors concerning the badness of the work put into these. Abraham’s death occurred in 1712, and it seems probable that even if he had had a longer life, the work of the printing-office would speedily have come to a close from inanition or from lack of intelligent direction.