In signal contrast to the honorable and candid course of Prof. CALDWELL, and to the candid examination, followed by eulogistic language of Prof. H. P. GATCHELL, ROBERT DALE OWEN, President ANDREW WYLIE, Rev. JOHN PIERPONT, Dr. SAMUEL FORRY, Prof. WM. DENTON, the eloquent Judge ROWAN, and a score of other eminently intellectual men, it is my duty to record the melancholy fact that the great majority of professional men, when tested, have manifested an entire apathy, if not a positive aversion, to the investigations and discoveries in which these momentous results have been reached. While no aversion, disrespect, or suspicion was shown toward myself, a stubborn aversion was shown to investigations that might have revolutionary results--proving that our false systems of education teach men not to think independently, but to adhere closely to precedent authority, fashion, popularity, and _habit_, which is the inertia of the mental world. The faculty of my alma mater (excepting Prof. Caldwell) refused to investigate the subject, even when invited by their Board of Trustees. The Boston Academy of Arts and Sciences, embracing the men at the head of the medical profession, pretended to take up the subject, but in a few hours dropped it, with polite compliments to myself, in 1842. The American Medical Association, in 1878, refused to entertain the subject because I could not coincide with them in my sentiments, and accept their code of bigotry. There was no formal action of the Association, but my friend, Prof. Gross, then recognized as the Nestor of the profession, and holding the highest position of authority, informed me semi-officially, very courteously, that none of my discoveries could ever be brought to the notice of the Association, because I did not accept their code. Thus (without mentioning other instances), I have stood before the public with a _demonstrable_ science, challenging investigation by critical opponents, who have so uniformly evaded or shrunk from the test that I have ceased to care for their opinions, while I still entertain as profound a respect as ever for the investigations of the candid and manly, among whom I never fail to find friendship and cordiality. Looking back forty-five years, I remember with extreme pleasure the friendly co-operation of ROWAN and CALDWELL. The American medical profession never had a more dignified, imposing, and high-toned representative than Prof. Caldwell. Nor was the legal profession anywhere ever adorned by a more commanding and gracious representative than the unsurpassed advocate, ROWAN, who was widely known as the "OLD MONARCH." The nobility of such men was shown in their noble bearing toward a dawning science, In which they saw the grandeur of the future. BUSINESS DEPARTMENT. COLLEGE OF THERAPEUTICS.