It opens with the marriage, in 1572, of Henry of Navarre and Margaret, sister of King Charles IX, which was intended to assuage the religious strife. But the Duke of Guise, the protagonist of the play, is determined to counterwork this policy, and with the aid of Catherine de Medicis, the Queen-Mother, and the Duke of Anjou (afterwards Henry III), he arranges the massacre of the Huguenots. Of the events of the fatal night we get a number of glimpses, including the murder of a Protestant, Scroune, by Mountsorrell (Chapman's Montsurry), who is represented as one of the Guise's most fanatical adherents. Charles soon afterwards dies, and is succeeded by his brother Henry, but "his mind runs on his minions," and Catherine and the Guise wield all real power. But there is one sphere which Guise cannot control--his wife's heart, which is given to Mugeroun, one of the "minions" of the King. Another of the minions, Joyeux, is sent against Henry of Navarre, and is defeated and slain; but Henry, learning that Guise has raised an army against his sovereign "to plant the Pope and Popelings in the realm," joins forces with the King against the rebel, who is treacherously murdered and dies crying, "_Vive la messe!_ perish Huguenots!" His brother, the Cardinal, meets a similar fate, but the house of Lorraine is speedily revenged by a friar, who stabs King Henry. He dies, vowing vengeance upon Rome, and sending messages to Queen Elizabeth, "whom God hath bless'd for hating papistry." It is easy to see how a play on these lines would have appealed to an Elizabethan audience, while Marlowe, whether his religious sympathies were engaged or not, realized the dramatic possibilities of the figure of the Guise, one of the lawlessly aspiring brotherhood that had so irresistible a fascination for his genius. But it is much more difficult to understand why, soon after the accession of James I, Chapman should have gone back to the same period of French history, and reintroduced a number of the same prominent figures, Henry III, Guise, his Duchess, and Mountsorrell, not in their relation to great political and religious outbreaks, but grouped round a figure who can scarcely have been very familiar to the English theatre-going public--Louis de Clermont, Bussy d'Amboise.[xii-1]