In studying the subject I have been greatly assisted by the masterful work of Roger Williams, so often referred to and quoted from; and I feel that a candid and careful perusal of that book will be a revelation to many. I know that some have endeavored to throw discredit upon some of the deductions which he makes from various statistics, but in the main they all teach a valuable lesson and are worth serious consideration, as they are taken from reliable sources. Realizing fully that the problem of the cause and proper treatment of cancer is a most profound one, which master minds have long wrestled with and which cannot be fully settled without much further study, these lectures are presented to the profession at large in the hope that they may be the means of helping some one threatened with or suffering from malignant disease; and also that they may possibly stimulate others to investigate even more diligently along the lines of the medical aspects of cancer. January, 1915. 531 Madison Avenue. CONTENTS PAGE LECTURE I NATURE OF CANCER 15 LECTURE II FREQUENCY AND GEOGRAPHICAL DISTRIBUTION OF CANCER 43 LECTURE III METABOLISM OF CANCER 70 LECTURE IV RELATION OF DIET TO CANCER 106 LECTURE V MEDICAL TREATMENT OF CANCER 135 LECTURE VI CLINICAL CONSIDERATIONS AND CONCLUSIONS 170 BIBLIOGRAPHY 211 INDEX 221 CANCER ITS CAUSE AND TREATMENT LECTURE I NATURE OF CANCER