Convinced that administration in candy form would be ideal for
children, the author took a number of years ago a course of instruction
with a candy-maker, in the hope of finding in the confectioner's art
some new form of pleasant administration for medicine. He made sulphur
taffy and cod-liver oil chocolate creams;[1] but these and a large
number of other attempts were unsuccessful. It may be of interest,
in this connection, to note that, in 1911, Sir James Sawyer[2]
published in "The Lancet" a process for the production of what he
calls "cremulae" or medicated chocolate creams. They were prepared by
evaporating a mixture of sugar and of milk to the consistency of paste,
in which various medicaments might be incorporated, and which is then
covered with chocolate, as in the popular chocolate drop. This is, as
will be seen, a troublesome process. The author's studies in the candy
shop seemed to point to "fondant" as the most suitable candy form for
purposes of medication. "Fondant", however, has the disadvantage of
becoming hard with age. Free from this objection and closely similar
to the "fondant" is a rather lightly compressed tablet made of finely
powdered cane sugar. And so finally the tablet form was chosen as
the best and most convenient for candy medication--a form which was
already in successful use, as has been stated, for the administration
of calomel and of phenolphthalein. For such tablets the term _tabellae
dulces_,[3] or sweet tablets, might be proposed.
CHAPTER II.
TABELLAE DULCES.
TO BE SUCCESSFUL, sweet tablets must meet the following requirements:
1. They must be perfectly delicious sweets, attractive in form, color,
and odor; and free from the slightest suspicion of disagreeable or
medicinal taste.
2. They must disintegrate rapidly in the mouth; for a sick child will
usually not suck candy as a healthy youngster would.
3. To constitute a real advance in therapeutics, it must be possible
for the average pharmacist to prepare them extemporaneously, so that
the physician may be able to fit the medicament to suit the case,
and that the pharmacist may not be forced to carry in stock a large
assortment of these more or less perishable goods.
Public-domain text, read in full here on John Shaqi.
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