Bartholini wrote to him again: "Your fame is growing from day to day, for your pen and your sharp eye know no rest." Later he wrote {145} again: "You may count upon the favor of the king as well as upon the applause of the learned." After three years at the University of Amsterdam, Steno returned to Copenhagen, where he published his "Anatomical Observations Concerning the Muscles and Glands." It was in this book that he announced his persuasion that the heart was a muscle. As he said himself, "the heart has been considered the seat of natural warmth, the throne of the soul; but if you examine it more closely, it turns out to be nothing but a muscle. The men of the past would not have been so grossly mistaken with regard to it, had they not preferred their imaginary theories to the results of the simple observation of nature." It is easy to understand that this observation created a very great sensation. It had much to do with overthrowing certain theoretic systems of medicine, and nearly a century later the distinguished physiologist, Haller, did not hesitate to proclaim the volume in which it occurs, as a "golden book." Stensen's studies in anatomy stamp him as an original genius of a high order, and this is all the more remarkable because his career occurs just in those years when there were distinguished discoverers in anatomy in every country in Europe. When Stensen began his work in anatomy, Harvey was still alive. The elder Bartholini, the first who ever established an anatomical museum, was another of his contemporaries. Among the names of distinguished anatomists {146} with whom Stensen was brought intimately in contact during the course of his studies in Holland, France and Italy are those of Swammerdam, Van Horne, and Malpighi. There is no doubt that his intercourse with such men sharpened his own intellectual activity, and increased his enthusiasm for original investigation in contradistinction to the mere accumulation of information. His contemporaries, indeed, exhausted most of the adjectives of the Latin language in trying to express their appreciation of his acuity of observation. He was spoken of as _oculatissimus_--that is, as being all eyes, _subtilissimus, acutissimus, sagacissimus_ in his knowledge of the human body, and as the most perspicacious anatomist of the time. Leibnitz and Haller were in accord in considering him one of the greatest of anatomists. In later years this admiration for Stensen's genius has not been less enthusiastically expressed. Haeser, in his "History of Medicine," the third edition of which appeared at Jena in 1879, says: "Among the greatest anatomists of the seventeenth century belongs Nicholas Steno, the most distinguished pupil of Thomas Bartholini. Steno was rightly considered in his own time as one of the greatest of anatomical discoverers. There is scarcely any part of the human body the knowledge of which was not rendered more complete by his investigations."