According to Dr. Colombe[15], Coca is a potent factor in the treatment of syphilis.[16] "It is demonstrated that potassium iodide and potassium chlorate undergo double decomposition in the system, and thus interfere with each other's action. Coca, substituted for the chlorate under such circumstances, would not be open to the same objection. It would find its application, therefore, when the mixed treatment is found necessary." DISEASES OF THE THROAT, PHARYNX AND THE LARYNX. As regards the _anginæ_, the acute inflammations of the larynx and pharynx, we might repeat what has been said about inflammations of the mouth. In particular, the pain, so violent in certain _anginæ_, calls for this method of treatment. The same is true of the dysphagia which accompanies them. Charles Fauvel first recognized the virtues of Coca in the tingling of follicular _angina_ and the laryngeal pains of tuberculous subjects. In those cases he specifies Mariani's extract of Coca leaves in preference to solutions of Cocaine, which sometimes give rise to symptoms of poisoning. Dr. Rouquette[17] relates a case of tubercular laryngitis in which symptoms of poisoning showed themselves as early as the third day; the parts had been painted twice a day with a five-per-cent solution of Cocaine. Dr. Paul Legendre has quite recently mentioned anew the danger that may result from a too free use of Cocaine[18]. The case was that of an interne of the hospitals attacked with diphtheria who, in order that he might the better bear the spraying with caustics, had his throat painted with a solution of Cocaine. Toward the seventh day he experienced very grave symptoms of poisoning, and the painting had to be suspended. It is better, in cases of this sort, to prescribe extract of Coca, which answers the same purposes without the attendant danger of Cocaine. One of the greatest triumphs of extract of Coca is assuredly its action in dysphagia and in the vomiting of consumptives, as also in the vomiting of pregnancy. The first two complications are of the gravest kind, for they condemn to starvation patients whose only chance of safety lies in the activity of the digestive organs (Ch. Fauvel and Coupard). DISEASES OF THE STOMACH. Authors who have given attention to Coca speak very highly of its employment in gastralgia and tardy and laborious digestion. Demarle says on this subject: "Personally, I have found the use of Coca, either before or after eating, excellent for gastrodynia and pyrosis, to which I am subject; hardly have I swallowed the first bit of saliva when the whole unpleasant feeling disappears." Mantegazza speaks of its use in the same strain. The cephalic congestion which accompanies his digestion is relieved; he can work after eating without feeling any uneasiness.