Tonic and pectoral, _Pâte Mariani_ is a Lozenge very agreeable to the taste, which is prescribed daily with the greatest success by throat specialists for obstinate coughs, granular catarrh of the throat, and the various inflammations of the digestive and respiratory passages. Composed only of clarified gum, sugar and Coca, without a trace of opium or of any narcotic substances, it may be taken without danger at any hour of the day and in any quantity, without fear of its disturbing the digestion, since, on the contrary, it can only aid it. From six to ten of the Lozenges daily are the usual dose, but more may be taken if necessary. Its beneficial action is due to the happy combination of the emolient properties of pure gum-arabic and the tonic, astringent and analgesic properties of Coca. "_Pâte Mariani_ has a powerful tonic action on the larynx, and, like _Vin Mariani_, it is invaluable in cases of aphonia caused by feebleness or relaxation of the vocal cords. This property is of special advantage to singers and orators. _Pâte Mariani_ is a very valuable substitute in granular catarrh of the throat and throat affections in general, for chlorate of potassium pastilles and the various lozenges containing opium, etc., the _Pâte Mariani_ is more agreeable to the taste and produces anæsthetic and soothing effects." (_Gazette des Hopitaux._) PASTILLES MARIANI (COCA AND COCAINE). The _Pastilles Mariani_ are used in the same cases as the _Pâte_, from which they differ only by the addition of two milligrammes of Cocaine hydrochlorate to each pastille. Their action is much more intense and more rapid than that of the plain Coca Lozenges. The paroxysms of cough which are so frequent and so annoying to those who smoke tobacco to excess, are overcome as if by enchantment by the use of a few pastilles. Dose—Four to eight daily. This amount, however, may be exceeded, at the discretion of the physicians. THÉ MARIANI, OR CONCENTRATED EXTRACT OF COCA (TEA MARIANI). As its name indicates, Mariani's concentrated extract of Coca, or _Thé Mariani_, contains within a small bulk all the active principles of the Coca leaf. This extract, prepared in special apparatuses which prevent all alteration and preserve all its properties and all its aroma, answers entirely in the various modes of using Coca and constitutes a most scrupulously exact preparation in dose, the most convenient and the most active that could be desired. _Thé Mariani_ is capable of indefinite preservation and easy of transportation; it renders great service to persons who make mountain ascensions, fatiguing marches, or long journeys through unhealthy countries, and in fact in whatever may be called fatiguing work or pleasure. _Thé Mariani_ may be taken in the dose of from three to six teaspoonfuls in the course of the day, clear, or mixed with brandy, wine, water or milk, etc., hot or cold, in the latter cases sweetened to taste, if desired.