INFLAMMATION OF THE SESAMOID BONES differs slightly from the former. Pressure over the posterior region of the fetlock may cause the animal pain. The lameness shows a tendency to disappear with rest and reappear when the animal is again worked. Lameness is most prominent in some cases when the animal is first moved out. There may be a lack of local symptoms, such as heat and swelling. It is not uncommon for a bony enlargement to form on the sesamoid bone after a few months or a year. The following _treatment_ is recommended. Horses that have a poor quality of tendon and weak fetlocks and pasterns should not be used for breeding purposes. Careful driving would prevent a large percentage of injuries to tendons. The most important treatment for all injuries due to strains is rest. In all cases of severe strain to the structures in this region, it is very advisable to apply a plaster bandage. This should be left on for at least two weeks. When the acute inflammation has subsided, counterirritants may be applied. Either cold or hot applications are recommended. Cold applications are to be preferred at the beginning of the inflammation. Covering the tendons with a cold bandage, or with a heavy layer of antiphlogistin, is recommended. The horse should not be worked until after the tendons have had an opportunity to completely recover from the inflammation. CONTRACTED TENDONS, KNUCKLING-OVER.--New-born foals are sometimes unable to stand on their front feet because of the excessive knuckling-over. The colt may walk on the front of the pastern and fetlock. This sometimes results in severe injury to the skin and the underlying tissues. Knuckling-over in the mature horse is not always due to contracted tendons. It may occur as a symptom of inflammation of the flexor tendons, ligaments of the fetlock joint and the articulation as well. It may be noticed in animals that have ring-bone, or coffin-joint lameness. The most _common cause_ for this unsoundness is inflammation of the muscles and tendons of the flexors of the digit. As a result of long standing or severe inflammation, shortening of these structures occurs in consequence of the contraction of the inflammatory or cicatricial tissue. Knuckling-over in the newborn colt is commonly caused by a weakness or lack of innervation of the extensor muscle of the digit. Judging from the quick recovery that usually occurs, other causes for this condition are seldom present.