The importance of recognizing or diagnosing the seat and nature of the morbid change occurring in an organ or group of organs cannot be overestimated. Laymen do not comprehend the difficulty or importance of correctly grouping the signs or symptoms of disease in such a way as to enable them to recognize the nature of the disease. In order to be able to understand the meaning of the many symptoms or signs of disease, we must possess knowledge of the structure and physiological functions of the different organs of the body. We must be familiar with the animal when it is in good health in order to be able to recognize any deviation from the normal due to disease, and we must learn from personal observation the different symptoms that characterize the different diseases. Stockmen should be able to tell when any of the animals in their care are sick as soon as the first symptom of disease manifests itself, by changes in the general appearance and behavior. But in order to ascertain the exact condition a general and systematic examination is necessary. The examiner, whether he be a layman or a veterinarian, must observe the animal carefully, noting the behavior, appearance, surroundings, and general and local symptoms. Before making a _general examination_ of the animal it is well, if the examiner is not already acquainted with the history of the case (care, feed and surroundings), to learn as much about this from the attendant as is possible. Inquiry should be made as to the feeding, the conditions under which the animal has been kept, the length of time it has been sick, its actions, or any other information that may be of assistance in forming the diagnosis and outlining the treatment. The _general symptoms_ inform us regarding the condition of the different groups of body organs. A careful study of this group of symptoms enables us correctly to diagnose disease and inform ourselves as to the progress of long, severe affections. These symptoms occur in connection with the pulse, respirations, body temperature, skin and coat, visible mucous membranes, secretions and excretions, and behavior of the animal. _The local symptoms_ are confined to a definite part or organ. Swelling, pain, tenderness and loss of function are common local symptoms. A _direct_ symptom may also be considered under this head because of its direct relation to the seat of disease. It aids greatly in forming the diagnosis. Other terms used in describing symptoms of disease are _objective_, which includes all that can be recognized by the person making the examination; _indirect_, which are observed at a distance from the seat of the disease; and _premonitory_, which precede the direct, or characteristic symptoms. The _subjective_ symptoms include such as are felt and described by the patient. These symptoms are available from the human patient only.