This preparation, being a saturated infusion of plants and gums, &c., unknown to the medical profession, cannot be ascertained by any chemical analysis or examination. As the Proprietor has not developed the particulars relative to this discovery to any member of the profession, he is prepared to anticipate from the illiberal amongst their number a degree of censure; but he appeals from the tyranny of custom to the dictates of common equity and reason. If, in the course of medical research, any discovery is incidentally made, which offers to society the most important benefits, humanity appears to demand that it should be unreservedly communicated to the faculty, for the welfare of mankind: but, having devoted a considerable property and time in the conducting a series of experiments, totally unconnected with the customary routine of medical practice, in the completion of the discovery, the Author conceives that he is warranted to expect some remuneration by its sale, as a compensation for his labours. An invention is as much the property of its proprietor, as the estate he purchases or inherits. Society has a right to enjoy the advantage of his toil and skill—but, surely his labours have an equal claim on their patronage in return. The Public are sufficiently enlightened in the subject of medicine to be aware that the opposition which secret preparations have experienced from this quarter (though there are many exceptions to be made) arises entirely from interested motives, and they will decide accordingly. OF HOARSENESS, ARISING FROM COLD. HOARSENESS is not only a very distressing and painful complaint, but often extremely obstinate, and very difficult to cure by the customary means. A sense of roughness in the throat, with frequent attempts to clear it, is generally the first and most early symptom of the disease. It is attended with, or succeeded by irritation of the larynx, exciting a hard and dry cough, hoarseness of voice, with a sense of tightness across the chest, and sometimes with soreness and pain upon breathing deeply, or coughing. Lassitude, aching of the limbs, cold chills, and shiverings, are now apparent, with but little expectoration of the opaque matter that irritates the part; which, from neglect of the means of totally removing it, assumes other characters, and rapidly passes into inflammation of the lungs.