The fact of coadaptation, which was supposed to furnish the strongest argument against the principle of selection, in reality yields the clearest evidence in favour of it. We MUST assume it, BECAUSE NO OTHER POSSIBILITY OF EXPLANATION IS OPEN TO US, AND BECAUSE THESE ADAPTATIONS ACTUALLY EXIST, THAT IS TO SAY, HAVE REALLY TAKEN PLACE. With this conviction I attempted, as far back as 1894, when the idea of germinal selection had not yet occurred to me, to make "harmonious adaptation" (coadaptation) more easily intelligible in some way or other, and so I was led to the idea, which was subsequently expounded in detail by Baldwin, and Lloyd Morgan, and also by Osborn, and Gulick as ORGANIC SELECTION. It seemed to me that it was not necessary that all the germinal variations required for secondary variations should have occurred SIMULTANEOUSLY, since, for instance, in the case of the stag, the bones, muscles, sinews, and nerves would be incited by the increasing heaviness of the antlers to greater activity in THE INDIVIDUAL LIFE, and so would be strengthened. The antlers can only have increased in size by very slow degrees, so that the muscles and bones may have been able to keep pace with their growth in the individual life, until the requisite germinal variations presented themselves. In this way a disharmony between the increasing weight of the antlers and the parts which support and move them would be avoided, since time would be given for the appropriate germinal variations to occur, and so to set agoing the HEREDITARY variation of the muscles, sinews, and bones. ("The Effect of External Influences upon Development", Romanes Lecture, Oxford, 1894.)