children of insane parentage, who are perverse from the start? Will he say that the perverseness is only a 'badness' which should be whipped out of the child? But that has generally been thoroughly tried before the physician is consulted. Heterodox I know it is, but observed facts compel me to be heterodox with Prichard and Esquirol and Ray, with Morel and Griesinger and Maudsley, and I know not how many others, in recognising in some cases a condition of inherent defect born in the individual, and not a result of education--a condition which writers have recognised under various names as hereditary mental disorder, insane diathesis, insane temperament." The Guiteau trial so stimulated studies of degeneracy that two experts for the prosecution, A. McL. Hamilton[48] and H. M. Stearns,[49] later changed their views as to degeneracy, while C. L. Dana, a strong supporter of the Gray school in 1881, subsequently made valuable contributions to the literature of the degeneracy stigmata. The position then taken by Spitzka and Kiernan as to the cerebral basis of degeneracy was in 1882 supported by H. Howard,[50] of Montreal; Workman,[51] of Toronto; Kerlin,[52] of Pennsylvania; Osler,[53] of Baltimore; and C. K. Mills,[54] of Philadelphia. It was during 1881, moreover, that Jacobi made extensive studies of degeneracy in royalty and aristocracy,[55] as earlier had Ireland.[56] From the time of Itard degenerate phenomena in idiots had been traced to cerebral mal-development. Kerlin[57] pointed out that "epileptic change" in them was marked by moral alteration similar in explosive characters to that so frequently observed in criminals. In England students of idiocy like Clouston, Shuttleworth, Beach, Ireland, Langdon Down, and others, had early brought the recognition of its inter-relations with insanity, crime and neuroses into strong relief. To the studies of Bruce Thomson, Maudsley, and Nicolson, Tyndall[58] gave strong support from the actual experience of a governor of a great British prison, who found that the prisoners in his charge might be divided into three distinct classes: the first class consisted of persons who ought never to have been in prison; external accident and not internal taint had brought them within the grasp of the law, and what had happened to them might happen to most of us; they were essentially men of sound moral stamina, though wearing the prison garb. Then came the largest class, formed of individuals possessing no strong bias, moral or immoral, plastic to the touch of circumstances which would mould them into either good or evil members of society. Thirdly, came a class, happily not a large one, whom no kindness could conciliate and no discipline tame. They were sent into the world labelled "incorrigible," wickedness being stamped, as it were, upon their organisation.