Diabetes : $b Its cause and its treatment with insulin — John Shaqi
Diabetes : $b Its cause and its treatment with insulinWilder, Russell M. (Russell Morse)
Science
Diabetes : $b Its cause and its treatment with insulin
Wilder, Russell M. (Russell Morse)
Diabetes; Insulin
_Insulin now available for everyone._--Insulin can now be obtained
in every drug store and fortunately, thanks to wise provisions for
maintaining control of its manufacture arranged for by the University
of Toronto, it is everywhere of uniform strength. This matter of
constant strength is of the greatest importance. As will appear later,
danger attends its indiscriminate use, and the dose must be made to
match the amount of sugar derivable from the diet. Unless the strength
of various lots of insulin is constant, accurate treatment would be
impossible. This was recognized early by the workers in Toronto and,
to protect the public, it was decided that insulin must be patented
so that its manufacture could be restricted to those firms who
would permit the control of their products by an insulin committee
in Toronto. The firm of Eli Lilly and Company of Indianapolis put
their plant at the disposal of the insulin committee and assisted in
developing methods of large scale production. Subsequently, other firms
have been licensed, by the insulin committee, to make insulin.
* * * * *
The patenting of discoveries by physicians is usually frowned on by
physicians. It is opposed to the ethical code of the profession. The
patenting of insulin, however, does not violate this ethical code
because the patent, while secured in the name of Doctor Banting
and his associates, was given outright by them to the University of
Toronto to be used, not for any commercial advantage, but as a means to
guarantee that this splendid discovery would not be exploited by others
to its discredit.
_Insulin described._--Today, insulin, as sold, is a clear, watery
solution. A small vial contains 50, 100 or 200 units, as indicated on
the label. The strength of the unit is standard. A unit of insulin will
have a certain definite lowering effect on the sugar in the blood of a
normal animal. The rabbit is chosen as the test animal. In the patient
with diabetes, a unit of insulin will increase tolerance, that is, it
will add to the amount of sugar that can be utilized, from 0.5 gram to
4 grams, depending on the character of the diet and the presence or
absence of complications. The average patient uses between 10 and 30
units a day. The cost has been reduced to below one cent a unit, so
that insulin is now brought within the reach of everyone. Indeed, the
cost is negligible when we consider that patients who, without insulin,
were helpless invalids, dependent on relatives or charity, are now as
fit and strong as their neighbors, and able to work again.
THE CAUSE OF DIABETES
Public-domain text, read in full here on John Shaqi.
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