Disease and Its CausesCouncilman, W. T. (William Thomas)
Science
Disease and Its Causes
Councilman, W. T. (William Thomas)
Diseases -- Causes and theories of causation
Living matter is always individual, and this individuality is
expressed in slight structural variations from the type of the species
as shown in an average of measurements, and also in slight variations
in function or the reactions which living tissue shows towards the
conditions acting upon it. The anatomical variations are more striking
because they can be demonstrated by weight and measure, but the
functional variations are equally numerous. Thus, no two brains react
in exactly the same way to the impressions received by the sense
organs; there are differences in muscular action, differences in
digestion; these variations in function are due to variations in the
structure of living material which are too minute for our
comparatively coarse methods of detection. In the enormous complexity
of living matter it is impossible that there should not be minute
differences in molecular arrangement and to this such functional
variations may be due. Chemistry gives us a number of examples of
variations in the reaction of substances which with the same
composition differ in the molecular arrangement. Even in so simple a
mechanism as a watch there are slight differences in structure which
gives to each watch certain individual characteristics, but the type
as an instrument constructed for recording time remains. In the fusion
of the chromosomes of the male and female sexual cells, to which the
hereditary transmission of the ancestral qualities to the new
offspring is due, there are differences in the qualities of each, for
the individuality of the parents is expressed in the germ cells, and
the varying way in which these may fuse gives to the new cell
qualities of its own in addition to qualities which come from each
ancestor, and from remote ancestors through these. The qualities with
which the new organism starts are those which it has received from its
ancestors plus its individuality. The fact that the sexual cells are
formed from the early formed cells of the new organism which represent
all of the qualities of the fertilized ovum or primordial cell,
renders it unlikely that the new offspring will contain qualities
which the parents have acquired. The question of the inheritance of
characteristics which the parents have acquired as the result of the
action of environment upon them is one which is still actively
investigated by the students of heredity, but the weight of evidence
is opposed to this belief.
In the new organism the type of the species is preserved and the
variations from the mean to which individuality is due are slight. We
are accustomed to regard as variations somewhat greater departures
from the species type than is represented in individuality, but there
is no sharp dividing line between them.
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