Disease and Its CausesCouncilman, W. T. (William Thomas)
Science
Disease and Its Causes
Councilman, W. T. (William Thomas)
Diseases -- Causes and theories of causation
Very much wider departures from the species type are known as
mutations. Such variations and mutations, like individuality, may be
expressed in qualities which can be weighed and measured, or in
function, and all these can be inherited; certain of them known as
dominant characteristics more readily than others, which are known as
recessive. If these variations from the type are advantageous, they
may be preserved and become the property of the species, and it is in
this way that the characteristics of the different races have arisen.
Certain of the variations are unfavorable to the race. The varying
predisposition to infection which undoubtedly exists and may be
inherited represents such a variation. Tuberculosis is an instance of
this; for, while the cause of the disease is the tubercle bacillus,
there is enormous difference in the resistance of the body to its
action in different individuals. The disease is to a considerable
extent one of families, but while this is true the degree of the
influence exerted by heredity can be greatly overestimated. The
disease is so common that in tracing the ancestry of tuberculous
patients it is rare to find the disease not represented in the
ancestors. A further difficulty is that the environment is also
inherited. The child of a tuberculous parent has much better
opportunity to acquire the infection than a child without such an
environment [page 167]. Other diseases than the infectious seem to be
inherited, of which gout is an example. In gout there is an unusual
action of the cells of the body which leads to the formation and the
retention in the body of substances which are injurious. Here it is
not the disease which is inherited, but the variation in structure to
which the unusual and injurious action of the cells is due.
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