It was formerly customary in many quarters to speak of atrophic and hypertrophic cirrhosis. Now it is generally thought that any form will be large or small as growth and regeneration on the one hand, or contraction, atrophy and degeneration on the other, may be predominant at the time the organ is seen. It is perhaps misleading to judge by our notes of what happens, but it is curious that in the thirty-two cases, the pathologist could state only in seventeen instances that the liver was larger or smaller than normal. This means therefore that the liver of cirrhosis need not deviate greatly from its customary size. Nine of the seventeen times the organ was considered smaller than normal, eight times it was greater. These variations did not strictly correspond to type, but the portal form, frequently called atrophic, was more often small than was the biliary form. Gastrointestinal disease accompanied cirrhosis in fourteen instances. Nephritis was present nineteen times. The spleen was enlarged six times, in all of which definite evidence of infection existed in the body. Choledochitis existed four times, twice with biliary cirrhosis, twice with perilobular fibrosis; cholecystitis existed twice, once in a monkey, and once in a bird with parasites. Pancreatitis was seen in three biliary cirrhoses and once in a perilobular fibrosis. The relation of the existence of cirrhosis to the presence of a gall- bladder is interesting. Among the thirty-two animals twenty-one have gall-bladders, eleven have not. The exact number of animals in our whole list with and without this structure, unfortunately cannot be given with exactness. As nearly as I can figure it out, sixteen per cent. of our animal posts have been on varieties without a gall-bladder, eighty-four per cent. with it. This would make the absence of this reservoir a factor favoring the development of cirrhosis since one-third of the cirrhoses are in groups devoid of this bag, yet these same groups supplied only one-sixth of the total postmortems. GALL STONES. Our experience with concrements in the biliary system is limited to six cases which can be detailed in brief. American Beaver ♀ (_Castor canadensis_) showed a soft purplish liver with groups of tortuous yellow lines; these prove to be groups of hepaticola with fatty degeneration around them, but successful regeneration is going on; bile ducts are not seriously involved over any great part of the organ; the bladder is distended greatly with thin, yellow-green fluid; duct is not patulous; common duct narrowed at middle and above this constriction lies a small concrement; bladder contains two large and several small pale yellow-green friable stones; mucosa injected and covered with mucopus; the pancreas is not affected.