About this time the doctor, reading an old medical book of the fifteenth century, was greatly struck by a method of treating disease called signature. To cure a diseased organ, it was only necessary to take from a sheep or an ox the corresponding organ in sound condition, boil it, and give the soup to the patient to drink. The theory was to cure like by like, and in diseases of the liver, especially, the old work stated that the cures were numberless. This set the doctor’s vivid imagination working. Why not make the trial? If he wished to regenerate those enfeebled by hereditary influences, he had only to give them the normal and healthy nerve substance. The method of the soup, however, seemed to him childish, and he invented in its stead that of grinding in a mortar the brain of a sheep, moistening it with distilled water, and then decanting and filtering the liquor thus obtained. He tried this liquor then mixed with Malaga wine, on his patients, without obtaining any appreciable result. Suddenly, as he was beginning to grow discouraged, he had an inspiration one day, when he was giving a lady suffering from hepatic colics an injection of morphine with the little syringe of Pravaz. What if he were to try hypodermic injections with his liquor? And as soon as he returned home he tried the experiment on himself, making an injection in his side, which he repeated night and morning. The first doses, of a gram only, were without effect. But having doubled, and then tripled the dose, he was enchanted, one morning on getting up, to find that his limbs had all the vigor of twenty. He went on increasing the dose up to five grams, and then his respiration became deeper, and above all he worked with a clearness of mind, an ease, which he had not known for years. A great flood of happiness, of joy in living, inundated his being. From this time, after he had had a syringe made at Paris capable of containing five grams, he was surprised at the happy results which he obtained with his patients, whom he had on their feet again in a few days, full of energy and activity, as if endowed with new life. His method was still tentative and rude, and he divined in it all sorts of dangers, and especially, that of inducing embolism, if the liquor was not perfectly pure. Then he suspected that the strength of his patients came in part from the fever his treatment produced in them. But he was only a pioneer; the method would improve later. Was it not already a miracle to make the ataxic walk, to bring consumptives back to life, as it were; even to give hours of lucidity to the insane? And at the thought of this discovery of the alchemy of the twentieth century, an immense hope opened up before him; he believed he had discovered the universal panacea, the elixir of life, which was to combat human debility, the one real cause of every ill; a veritable scientific Fountain of Youth, which, in giving vigor, health, and will would create an altogether new