Father MacDonald's education was finished in the College of Three Rivers, Canada, under the Sulpician Fathers. After his ordination he exercised the ministry in several places till sent by the Bishop of Boston to Manchester. Here he found his co-religionists and countrymen regarded as Helots, and far more despised by Yankee and Puritan than the slaves in the South by their rulers. The Irish were denied the privilege of sidewalks, and obliged, in order to avoid perpetual quarrels, to walk in the middle of the streets. Wherever they appeared, they were hissed and hooted, and "blood-hounds of hell" was the affectionate epithet the ubiquitous small boy bestowed on them. Previous to Father MacDonald's arrival, Father Daly, whose parish included nearly all New Hampshire and Vermont, used to say Mass in Manchester with unfailing regularity every three months. On one of these occasions, the floor of the temporary chapel gave way, and priest, altar, and congregation, were precipitated into the cellar. Providentially, beyond a few bruises and abrasions, no one was injured. The previous day, the bigots having heard that Mass was to be said in the room, had cut the supports from under the floor. To these people, a priest was an object of hatred and scorn, whom they believed it would be a good work to kill, and Father MacDonald settled among them at the risk of his life. But when duty was in question, he knew not fear. _The servant is not greater than his master_, he would say: _If they have persecuted me they will persecute you also_. It was in vain they used every means their perverse ingenuity suggested to intimidate this dangerous papist. They even began to like him. Slowly but surely, he won his way among them, and within a year of his arrival he was able to hire the Granite Hall as a temporary chapel. In 1849, he built a church on a square purchased with his own patrimony, at the corner of Union and Merrimac Streets.