Assuming that the soil and climate of the situation selected are suitable for the growing of drug plants, it does not necessarily follow that they can be produced at a profit. The cost of production and marketing may be greater than the amount received for the crop when it is sold. Some drug plants not well suited for cultivation on a large scale may be found profitable when grown on small areas as a side line. On the other hand, some may be produced more cheaply when cultivated on a scale large enough to warrant the use of labor-saving devices than when grown on small areas with the aid of hand labor alone. The value of land, the cost and availability of labor, and the possible returns from other crops are all factors to be considered carefully. On account of the variation in these factors according to locality, the same crop might prove to be profitable in one location and unprofitable in another. It is for these reasons that unqualified statements concerning the ease and profitableness of drug plant growing should not be taken too seriously. SOME DRUG PLANTS SUITABLE FOR CULTIVATION IN THE UNITED STATES. The number of drug plants which may be grown in the United States is large, although the same plants are not equally adapted to the conditions of soil and climate prevailing in different sections. Often the most suitable plants for a particular locality can not be foretold, especially in those situations where no attempts have yet been made to grow them. In such cases it is well to select for cultivation plants which thrive elsewhere under conditions most closely resembling those of the new situation in which it is proposed to grow them. The success with which ordinary field or garden crops can be grown will in general indicate the possible suitability of a given location for growing many medicinal plants. Since a number of native medicinal plants which in their wild state are restricted to certain localities have been successfully cultivated in situations far beyond their natural range, there are good reasons for believing that many such plants will thrive in sections where they are not now grown. However, good results can scarcely be expected unless the plants are placed under conditions similar to those in which they normally thrive. In suitable soil and under favorable weather conditions the following drug plants have been found to thrive well under cultivation in numerous places in the Central and Eastern States and will probably be found suitable for cultivation in many other situations if the difference in climatic conditions is not too great: Anise. Conium. Elecampane. Sage. Belladonna. Coriander. Fennel. Stramonium. Camomile. Digitalis. Henbane. Tansy. Caraway. Dill. Horehound. Thyme.