almost indefinite prolongation of time, even for a minute. The paroxysms already alluded to were not accompanied with muscular relaxation. About a quarter before nine o’clock I was standing at the door, anxiously watching for the doctor, and when the spells would come on I would remain standing, leaning slightly, perhaps, against the doorway. After awhile I saw a man approaching, whom I took to be the doctor. The sound of his steps told me he was walking very rapidly, and he was under a gas-lamp, not more than one-fourth of a square distant, yet he appeared a vast distance away, and a corresponding time approaching. This was the only occasion in which I noticed an exaggeration of distance; in the room it was not perceptible. My extremities now began to grow cold, and I went into the house. I do not remember further, until I was aroused by the doctor shaking or calling me. Then intellection seemed pretty good. I narrated what I had done and suffered, and told the doctor my opinion was that an emetic was indicated, both to remove any of the extract still remaining in my stomach, and also to arouse the nervous system. I further suggested our going into the office, as more suitable than the parlor, where we then were. There was at this time a very marked sense of numbness in my limbs, and what the doctor said was a hard pinch produced no pain. When I attempted to walk up-stairs my legs seemed as though their lower halves were made of lead. After this there were no new symptoms, only an intensifying of those already mentioned. The periods of unconsciousness became at once longer and more frequent, and during their absence intellection was more imperfect, although when thoroughly aroused I thought I reasoned and judged clearly. The oppressive feeling of impending death became more intense. It was horrible. Each paroxysm would seem to have been the longest I had suffered; as I came out of it a voice seemed constantly saying, ‘You are getting worse; your paroxysms are growing longer and deeper; they will overmaster you; you will die.’ A sense of personal antagonism between my will power, as affected by the drug, grew very strong. I felt as though my only chance was to struggle against these paroxysms—that I must constantly arouse myself by an effort of will; and that effort was made with infinite toil and pain. I felt as if some evil spirit had control of the whole of me, except the will power, and was in determined conflict with that, the last citadel of my being. I have never experienced anything like the fearful sense of almost hopeless anguish and utter weariness which was upon me. Once or twice during a paroxysm I had what might be called nightmare sensations; I felt myself mounting upward, expanding, dilating, dissolving into the wide confines of space, overwhelmed by a horrible, rending, unutterable despair. Then, with tremendous effort, I seemed to shake this off, and to start up with the shuddering thought,