Respiration is rarely affected. In some cases there is shortness of breath on walking fast or going up a long flight of stairs. A low grade bronchitis sometimes exists, as also a short, hacking cough, that seems to come chiefly from irritation in the throat. THE CIRCULATION. Circulation is often affected but chiefly through the agency of the nervous system; witness the flushing of the face, and flashes of heat over the body, followed by a cold, exhausting sweat. There is often irregular and weakened action of the heart, and congestion of the brain. The albuminuria already spoken of is due, in all likelihood, to an affection of the vessels of the kidneys, through the nerves supplying them. The blood itself, owing to a general condition of malnutrition and imperfect digestion, is unquestionably deteriorated. In some cases the vessels rupture, giving us purpuric spots on the body and hemorrhage from the kidneys and bowels. Dropsy, which sometimes occurs, is due, in the majority of instances, to variable blood pressure, and a diseased condition of the walls of the vessels, permitting the easy transudition of the watery element of the blood. Headache, flushing of the face, flashes of heat and the like, from suppression of the menses, is seen during the early period of morphia addiction, but later nothing but the nervous symptoms attendant upon this condition are manifested. THE MIND. Early in the use of morphia the effects upon the mind are simply those of pleasant exhilaration, a feeling of perfect contentment, good will toward all, increased conversational power and stimulation of the imaginative faculties. Sleep is preceded by a period of luxurious drowsiness, fertile in pleasant retrospective and magnificent anticipation. There is total banishment of pain and care. It is, indeed, the ideal life of a dreamer, moulded and modified according to the temperament and intellectual tendencies of the individual.