The answer to this question is not so obvious as might at first be expected. There were in the Lancashire of Elizabeth’s days two secret presses. From one there issued a number of Roman Catholic books. This was probably located at Lostock, the seat of the Andertons. The other was the wandering printing-press, which gave birth to the attacks of Martin Marprelate upon the Anglican Episcopate. This was seized by the Earl of Derby in Newton Lane, near Manchester. The printers thus apprehended were examined at Lambeth, 15th February, 1588, when Hodgkins and his assistants, Symms and Tomlyn, confessed that they had printed part of a book entitled, “More Work for the Cooper.” “They had printed thereof about six a quire of one side before they were apprehended.” The chief controller of the press, Waldegrave, escaped. In these poor persecuted printers we must recognise the proto-typographers of Manchester. No trace remains of “More Work for the Cooper.” The sheets that fell into the hands of the authorities do not appear to have been preserved. Putting aside the claims of this anti-prelatical treatise, we have to pass from the sixteenth to the eighteenth century. Many tracts and books by local men, and relating to local affairs, were printed before 1719, but that appears to be the date of the first book printed in Manchester. The title page is here reproduced:—“Mathematical Lectures; being the first and second that were read to the Mathematical Society at Manchester. By the late ingenious Mathematician John Jackson. ‘Who can number the sands of the Sea, the drops of Rain, and the days of Eternity?’—Eccles. i., 2. ‘He that telleth the number of the Stars and calleth them all by their Names.’—Psalm cxlvii., 4. Manchester; printed by Roger Adams in the Parsonage, and sold by William Clayton, Bookseller, at the Conduit, 1719.” (Octavo.) The claims of Jackson’s “Lectures” were stated by the present writer in _Notes and Queries_ (see fourth series, iii., 97, and vii., 64), and in his “Handbook to the Public Libraries of Manchester and Salford.” Some further correspondence appeared in _Local Gleanings_ (vol. i., p. 54), and an extract was given from one of William Ford’s catalogues, which, if accurate, would show that there was a local press at work in 1664. Ford has catalogued a book in this fashion:—“A Guide to Heaven from the Word; Good Counsel how to close savingly with Christ; Serious Questions for Morning and Evening; Rules for the due observance of the Lord’s Day. Manchester, printed at Smithy Door, 1664. 32mo.”