a romance for its interesting detail, though melancholy with its tale of pain and death. He shows that there is evidently a specific poison which breeds and multiplies in the living human body, and that this process of breeding and multiplying constitutes the fever itself. This essentially is its contagiousness, the communication from body to body of the specific matter or germ, which when bred and multiplied produces the fever. This he called the master-fact in its history. He further believed that all the emanations from the typhoid patient are in a certain degree infectious, but that what is cast off from the intestine is incomparably more virulent than anything else. Wherever no sufficient provision was made for preventing such material from contaminating the soil and air of the inhabited area around, notwithstanding the most spacious rooms, the freest ventilation, and careful nursing, he found there was no real security against the spread of the fever. The fact alleged against Dr. Budd’s views, that typhoid is seldom taken by attendants on the sick, does not at all militate against his teaching, for unless they received into their system through milk, water, food, or air, some of the specific poison of typhoid, they would certainly not suffer. In 1842 Dr. Budd settled in Clifton, and was in 1847 elected Physician to the Bristol Royal Infirmary. He lectured for a number of years in the Bristol Medical School, and worked incessantly at maturing and propagating his views on the nature and mode of propagation of zymotic disease. He was no mere theorist, but in all his pursuits had most practical objects in view, seeking to enforce on his medical brethren, public authorities as well as private persons, the urgent necessity of the most careful, well-advised, and continuous methods of disinfection. He was in effect a great sanitarian and champion of preventive medicine. Pure water was one of his great panaceas. The Bristol Waterworks were among his cherished objects of promotion and watchfulness. His remarkable clearness of vision and strength of conviction made him somewhat impatient of the strenuous opposition with which his views were met. For a long period he was almost alone in his uphill fight. He did not fully put his views before the profession till 1857-60, when he published a series of papers in the _Lancet_, afterwards embodied in his work on typhoid fever; but he had long before taught them in the Bristol Medical School, and practically acted upon them himself. During the depressing period of opposition which he encountered, almost the only sympathy he could count on was that of the late Sir Thomas Watson, who encouraged him greatly, believing his investigations to be of priceless value. Cheered in this way, Budd continued to promulgate his views, dogmatically it is true, but in a manner singularly attractive, for he had a natural kindliness of disposition and freedom from all jealousy. His impressive eloquence was not more