The discoveries of Columbus awakened a spirit of enterprise in Spain which continued in full force for a century; adventurers flocked eagerly across the Atlantic, and discovery followed discovery in rapid succession. Many of the companions of Columbus continued his work. Vicente Yanez Pinzon in 1500 reached the mouth of the Amazon. In the same year Alonso de Ojeda, accompanied by Juan de la Cosa, from whose maps we learn much of the discoveries of the 16th century navigators, and by a Florentine named Amerigo Vespucci, touched the coast of South America somewhere near Surinam, following the shore as far as the Gulf of Maracaibo. Vespucci afterwards made three voyages to the Brazilian coast; and in 1504 he wrote an account of his four voyages, which was widely circulated, and became the means of procuring for its author at the hands of the cartographer Waldseemuller in 1507 the disproportionate distinction of giving his name to the whole continent. In 1508 Alonso de Ojeda obtained the government of the coast of South America from Cabo de la Vela to the Gulf of Darien; Ojeda landed at Cartagena in 1510, and sustained a defeat from the natives, in which his lieutenant, Juan de la Cosa, was killed. After another reverse on the east side of the Gulf of Darien Ojeda returned to Hispaniola and died there. The Spaniards in the Gulf of Darien were left by Ojeda under the command of Francisco Pizarro, the future conqueror of Peru. After suffering much from famine and disease, Pizarro resolved to leave, and embarked the survivors in small vessels, but outside the harbour they met a ship which proved to be that of Martin Fernandez Enciso, Ojeda's partner, coming with provisions and reinforcements. One of the crew of Enciso's ship, Vasco Nunez de Balboa, the future discoverer of the Pacific Ocean, induced his commander to form a settlement on the other side of the Gulf of Darien. The soldiers became discontented and deposed Enciso, who was a man of learning and an accomplished cosmographer. His work _Suma de Geografia_, which was printed in 1519, is the first Spanish book which gives an account of America. Vasco Nunez, the new commander, entered upon a career of conquest in the neighbourhood of Darien, which ended in the discovery of the Pacific Ocean on the 25th of September 1513. Vasco Nunez was beheaded in 1517 by Pedrarias de Avila, who was sent out to supersede him. This was one of the greatest calamities that could have happened to South America; for the discoverer of the South sea was on the point of sailing with a little fleet into his unknown ocean, and a humane and judicious man would probably have been the conqueror of Peru, instead of the cruel and ignorant Pizarro. In the year 1519 Panama was founded by Pedrarias; and the conquest of Peru by Pizarro followed a few years afterwards. Hernan Cortes overran and