Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
SPUTUM IN BLOOD, LUNGS OR BRONCHUS
AT AUTOPSY
Autopsy 240 Pneum. IV Pneum. IV
246 Pneum. atyp. II, B. inf.
247 Pneum. IV, B. inf. Pneum. IV
250 Pneum. atyp. II, B. inf. Pneum. atyp. II
253 Pneum. atyp. II Pneum. II
285 Pneum. atyp. II, B. Inf. S. hem., B. inf.
288 S. hem., B. inf. S. hem., B. inf.
291 Pneum. IV, B. inf. Staph., B. inf.
300 Pneum. atyp. II, B. inf. Pneum. atyp. II, B. inf.
312 Pneum. IV, S. hem., B. inf. S. hem., B. inf.
346 Pneum. IV, B. inf. S. hem., B. inf.
In 2 instances (Autopsies 285 and 346) among this small group of cases,
pneumococci but no hemolytic streptococci were found in the sputum
several days before death, whereas death occurred as the result of
secondary invasion with hemolytic streptococci and no pneumococci were
found at autopsy. It is probable that this sequence of events is not
uncommon. B. influenzæ finds its way into the bronchi and pneumococci
follow it; pneumonia limited to peribronchiolar alveoli may occur in
consequence of this invasion. Later hemolytic streptococci may follow
the same path and cause death with bacteremia.
=Hemorrhagic Peribronchiolar Consolidation.=—Peribronchiolar pneumonia
accompanied by diffuse accumulation of blood within the alveoli is one
of the most frequent complications of influenza. The lung tissue is
laxly consolidated, and on section there is a homogeneous dull deep red
background upon which are seen small gray spots (1.5 to 2 mm. in
diameter) grouped in clusters about the smallest bronchi (Fig. 5). Wide
areas of lung tissue are implicated and the lesion is more common in the
dependent parts of the lung than elsewhere. In common with other forms
of bronchopneumonia the lesion is in most instances associated with
changes in the bronchi; in 55 instances of hemorrhagic bronchiolar
pneumonia purulent bronchitis was found in 43 instances; it is
noteworthy that purulent bronchitis often is not evident in the presence
of pulmonary edema and edema is not infrequent with this pneumonic
lesion.
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