Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
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AUTOPSY │ DURATION OF │ BLOOD │ LUNGS │ BRONCHUS
│ ILLNESS │ │ │
───────────┼──────────────┼──────────────┼──────────────┼──────────────
420 │11 days │S. hem. │S. hem., B. │
│ │ │ inf., S. │
│ │ │ aur. │
402 │14 days │Pneum. IV, │ │
│ │ S.hem. │ │
370 │17 days │ │S. aur. │S. aur.,
│ │ │ │ Pneum. IV,
│ │ │ │ B. inf.
457 │17+ days │ │ │Pneum. IV, B.
│ │ │ │ inf.
421 │19 days │S. hem. │Pneum. IV, S. │
│ │ │ hem. │
445 │27 days │S. hem. │Pneum. IV, S. │S. aur.
│ │ │ aur. │
473 │28+ days │Pneum. III │S. vir. │B. inf., S.
│ │ │ │ vir.,
│ │ │ │ staph., M.
│ │ │ │ catarr.
499 │36 days │S. hem. │ │S. hem. B.
│ │ │ │ inf.
───────────┴──────────────┴──────────────┴──────────────┴──────────────
Thrombosis of lymphatics in the wall of bronchi adjacent to blood
vessels and in interlobular septa occurs, and occasionally organization
of the fibrinous plug within the lymphatic is in progress (Autopsies
283, 425 and 463). Fibroblasts and capillaries penetrate from the wall
of the lymphatic into a mass of hyaline fibrin which fills the lumen.
=Unresolved Bronchopneumonia.=—The most common type of pneumonic lesion
following influenza is characterized by acute inflammation of the
alveoli immediately adjacent to the bronchioles and the lesion is
associated in many instances with hemorrhage or edema. If this lesion
persists unresolved during several weeks, evidences of chronic
inflammation are found. Peribronchial, perivascular and interlobular
connective tissue is thickened and richly infiltrated with lymphoid and
plasma cells, large mononuclear cells and many young fibroblasts.
Interalveolar septa adjacent to the walls of bronchi and between alveoli
surrounding inflamed bronchioles are implicated in the process.
Interstitial changes characterize the lesion only in its late stage. It
appears undesirable to give the name “interstitial pneumonia” to the
early stage of a lesion which begins and in most instances terminates as
an acute relatively superficial inflammation of the bronchi, bronchioles
and peribronchiolar alveoli.
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