Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
Chronic bronchopneumonia is often overlooked at autopsy because newly
formed connective tissue is not present in sufficient quantity to
attract attention (Fig. 26). When the lesion is advanced conspicuous
gray white patches of fibrous tissue may be seen about the bronchi
(Autopsy 487; Fig. 27) and interlobular septa may be obviously thickened
(Autopsy 472). The most distinctive feature of the lungs is the presence
of small, firm, gray or yellowish gray nodules of consolidation which
resemble miliary tubercles. They represent the peribronchiolar patches
of bronchopneumonia present during the acute stage and have assumed the
well-defined outline and firm consistence of tubercles because
polynuclear leucocytes and red blood corpuscles have in large part
disappeared, interstitial tissue is increased, and exudate is in process
of organization. These nodules are grouped in clusters about the small
bronchi.
With unresolved bronchopneumonia the lungs are very voluminous and fail
to collapse after they are removed from the chest and in some instances
even after incision. The air containing tissue is usually dry. In our
autopsies the lungs have been pink in color and often free from coal
pigment, because those suffering with pneumonia have been in
considerable part men from rural districts. Thick mucopurulent material
exudes from the small bronchi which have been cut across; purulent
bronchitis has been present in 20 of 21 instances of chronic
bronchopneumonia. Bronchiectasis has been present in 13 instances;
dilatation is often advanced, so that throughout the lungs are found
bronchi with no cartilage distended to a diameter of 0.5 cm. In addition
to the firm peribronchiolar tubercle-like nodules of consolidation there
are scattered patches of gray lobular or confluent lobular
consolidation. Yellowish nodules, grouped about bronchi and resembling
those found elsewhere in air containing tissue, are occasionally seen
scattered upon the cut surface of a patch of gray, confluent lobular
consolidation (Autopsies 421, 423, 431).
[Illustration:
Fig. 26.—Unresolved bronchopneumonia with tubercle-like nodules of
peribronchiolar consolidation best seen in lower lobe;
bronchiectasis. Autopsy 425.
]
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