Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
Microscopic examination demonstrates the presence of those changes which
have been described in association with chronic bronchitis and
bronchiectasis. There is abundant new formation of fibrous tissue about
the bronchi of small and medium size, thickening of adjacent
interalveolar walls and incorporation of alveoli into the thickened
bronchial wall (Figs. 27, 28, 30, and 31). In half of the instances of
chronic bronchopneumonia there has been peribronchial fibrinous
pneumonia, and organization of fibrin within the alveoli is usually well
advanced. In one instance (Autopsy 487; Figs. 27 and 28) after an
illness of fifty-five days this process has resulted in the formation of
conspicuous patches of firm, grayish white fibrous tissue surrounding
dilated bronchi. Organization of fibrinous exudate within the lung has
not been limited to the alveoli but has occurred in the bronchioles as
well. Organizing bronchiolitis has been present in 5 instances
(Autopsies 370, 402, 457 and 473).
Increase of fibrous tissue occurs about the blood vessels and in the
septa between the lobules, which are infiltrated with mononuclear
wandering cells and fibroblasts. Dilatation and thrombosis of the
lymphatic vessels have occurred in both situations, and in 3 instances
(Autopsies 283, 425 and 463) organization of these fibrinous thrombi has
occurred.
[Illustration:
Fig. 27.—Unresolved pneumonia with peribronchial formation of fibrous
tissue; bronchiectasis. Autopsy 487.
]
[Illustration:
Fig. 28.—Unresolved pneumonia with bronchiectasis showing new
formation of fibrous tissue about a greatly dilated bronchus of
which the epithelial lining has been lost. Autopsy 487.
]
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