Epitome of the Pharmacopeia of the United States and the National Formulary: With CommentsHewlett, Albion Walter
Science
Epitome of the Pharmacopeia of the United States and the National Formulary: With Comments
Hewlett, Albion Walter
Medicine -- Formulae, receipts, prescriptions; Pharmacopoeias -- United States
=Acidum Trichloraceticum (Acid. Trichloracet.), Trichloracetic Acid,
U.S.P.=--CCl{3}.COOH.
Colorless, deliquescent crystals with a slight characteristic odor.
Miscible with water and with alcohol.
ACTION AND USES: Caustic, for the removal of warts and
other skin blemishes. Used also as local hemostatic.
=Aconitina (Aconitin.), Aconitine, U.S.P.=--An alkaloid obtained from
aconite.
A white, odorless powder. Very slightly soluble in water, soluble
in alcohol (1:28) and in ether (1:65).
ACTION AND USES: Similar to those described under
aconite. As several alkaloidal preparations of aconite, of
varying activity, are sold under the name of aconitine, its
use is not advisable.
DOSAGE: 0.15 mg. or 1/400 grain (U.S.P.).
_Oleatum Aconitinae (Oleat. Aconitin.), Oleate of Aconitine,
N.F._--Aconitine (2%) in oleic acid and olive oil.
USES: Without advantage over aconite preparations for
external application.
=*Aconitum (Aconit.), Aconite, U.S.P.= (Monkshood, Aconite Root, Aconiti
Tuber, P.I.).--A tuberous root, yielding about 0.5 per cent. of
ether-soluble alkaloids; also assayed biologically. Physicians should
specify preparations that have been assayed biologically, since the
alkaloidal assay is not a reliable index of activity.
ACTION AND USES: Slows the pulse and lowers the blood
pressure, but this action in therapeutic doses is uncertain.
Used in the treatment of febrile colds; also for counter-irritation,
in the form of the tincture. Used also as a local
anesthetic, and by some still believed to be useful in the
treatment of the symptoms arising from excessive cardiac
hypertrophy. Toxic symptoms may occur from local
absorption.
DOSAGE: 0.03 Gm. or 1/2 grain (U.S.P.); not used as
such.
_Extractum Aconiti (Ext. Aconit.), Extract of Aconite, U.S.P._ (Powdered
Extract of Aconite).--Yields about 2 per cent. of ether-soluble
alkaloids. Biologically assayed by producing death in the guinea-pig.
DOSAGE: 0.01 Gm. or 1/6 grain (U.S.P.). Physicians
who prescribe extract of aconite should specify the biologically
assayed product.
_Fluidextractum Aconiti (Fldext. Aconit.), Fluidextract of Aconite,
U.S.P._--Aconite (100%), yielding about 0.5 per cent. of alkaloids.
Absolute alcohol content about 70 per cent. Biologically assayed by
producing death in the guinea-pig.
DOSAGE: 0.03 Cc. or 1/2 minim (U.S.P.). Physicians
who prescribe fluidextract of aconite should specify the
biologically assayed product. Best to use the tincture.
_Linimentum Aconiti et Chloroformi (Lin. Aconit. et Chlorof.), Liniment
of Aconite and Chloroform, N.F._--Fluidextract of aconite (4.5%), in
alcohol, chloroform and soap liniment.
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