I have used this medicine in cases where I had good evidence of the presence of tubercles in the lungs, and I do not doubt that it will be found to be serviceable in the incipient stages of the disease. But I much question whether it will prove even innocent in the more advanced periods of tubercles, when extensive disorganization has taken place in the lungs. Some cases in which I have prescribed it, were benefitted in so marked a manner as to have inspired me with hopes of having at length found a remedy for that hitherto intractable and cruel malady. Other cases, on the contrary, seemed to be much aggravated by its use. If I may judge from the cautious expressions of Dr. Baron, in his work on tuberculous disease, this is nearly the result of his experience also. It is much to be desired that we had sufficient data for distinguishing the cases in which its use is beneficial, inert, and injurious. As yet, the results I have obtained do not entitle me to come to any very definite conclusion on this subject. Mr. Haden, in his translation of Magendie’s Pharmacopœia, has given the history of a case of affection of the chest, in which he seems evidently to think that tubercles were removed by the agency of iodine. I am glad to find this case stated by Mr. Haden with his characteristic candour and caution. It is much to be desired that a series of such cases were published. They would form the materials on which a just estimate of the powers of this medicine might be formed. I trust to be able, at no distant period, to give the result of my experience in this disease to the public, in such a manner as to establish what are the real virtues of iodine in the cure of pulmonary tubercles. At present, there is certainly sufficient ground for making a cautious trial of its powers; but, if I may trust to my own experience, it is impossible to use it with too much circumspection.