Human wisdom makes as ill use of her talent, when she exercises it in rescinding from the number and sweetness of those pleasures that are naturally our due, as she employs it favourably and well in artificially disguising and tricking out the ills of life, to alleviate the sense of them. Had I ruled the roast, I should have taken another and more natural course, which, to say the truth, is both commodious and holy, and should, peradventure, have been able to have limited it too; notwithstanding that both our spiritual and corporal physicians, as by compact betwixt themselves, can find no other way to cure, nor other remedy for the infirmities of the body and the soul, than by misery and pain. To this end, watchings, fastings, hair-shirts, remote and solitary banishments, perpetual imprisonments, whips and other afflictions, have been introduced amongst men: but so, that they should carry a sting with them, and be real afflictions indeed; and not fall out as it once did to one Gallio, who having been sent an exile into the isle of Lesbos, news was not long after brought to Rome, that he there lived as merry as the day was long; and that what had been enjoined him for a penance, turned to his pleasure and satisfaction: whereupon the Senate thought fit to recall him home to his wife and family, and confine him to his own house, to accommodate their punishment to his feeling and apprehension. For to him whom fasting would make more healthful and more sprightly, and to him to whose palate fish were more acceptable than flesh, the prescription of these would have no curative effect; no more than in the other sort of physic, where drugs have no effect upon him who swallows them with appetite and pleasure: the bitterness of the potion and the abhorrence of the patient are necessary circumstances to the operation. The nature that would eat rhubarb like buttered turnips, would frustrate the use and virtue of it; it must be something to trouble and disturb the stomach, that must purge and cure it; and here the common rule, that things are cured by their contraries, fails; for in this one ill is cured by another.