In some instances, however, the disease seems to be purely local in character, and to be entirely independent of any constitutional or predisposing condition. The view recently advanced that the disease is of parasitic nature and contagious has been steadily gaining ground. #What is the pathology of seborrh[oe]a?# Seborrh[oe]a is a disease of the sebaceous glands, and probably often involving the sweat-glands also; its products, as found upon the skin, consisting of the sebaceous secretion, epithelial cells from the glands and ducts, and more or less extraneous matter. Not infrequently evidences of superficial inflammatory action are also to be found, and it is especially for this type that the name eczema seborrhoicum is most appropriate. In long-continued and neglected cases slight atrophy of the gland-structures may occur. #With what diseases are you likely to confound seborrh[oe]a?# Upon the scalp, with eczema and psoriasis; upon the face, with lupus erythematosus and eczema; and upon the trunk, with psoriasis and ringworm. As a rule, the clinical features of seborrh[oe]a are sufficiently characteristic to prevent error. #What are the differential points?# Eczema, psoriasis, and lupus erythematosus are diseases in which there are distinct _inflammatory symptoms_, such as thickening and infiltration and redness; moreover, psoriasis, and this holds true as to ringworm also, occurs in sharply-defined, circumscribed patches, and lupus erythematosus has a peculiar violaceous tint and an elevated and marginate border. A microscopic examination of the epidermic scrapings would be of crucial value in differentiating from ringworm. Quite frequently, especially in the interscapular and sternal regions, the segmental configuration constitutes an important feature of seborrh[oe]a--of the eczema seborrhoicum variety. #What is the prognosis in seborrh[oe]a?# Favorable. All types are curable, and when upon the non-hairy regions, usually readily so; upon the scalp it is often obstinate. Relapses are not uncommon. In those cases of seborrh[oe]a capitis which have been long-continued or neglected, and attended with loss of hair, this loss may be more or less permanent, although ordinarily much can be done to promote a regrowth (see _Treatment of Alopecia_). #How would you treat seborrh[oe]a of the scalp?# By constitutional (if indicated) and local remedies; the former having in view correction or modification of the predisposing factor or factors, and the latter removal of the sebaceous accumulations and the application of mildly stimulating antiseptic ointments or lotions. #What constitutional remedies are commonly employed?# The various tonics, such as iron, quinine, strychnia, cod-liver oil, arsenic, the vegetable bitters, laxatives, malt and similar preparations. The line of treatment is to be based upon indications. #How do you free the scalp of the sebaceous accumulations?#