The symptoms of cutaneous disease may be objective, subjective or both; and in some diseases, also, there may be systemic disturbance. #What do you mean by objective symptoms?# Those symptoms visible to the eye or touch. #What do you understand by subjective symptoms?# Those which relate to sensation, such as itching, tingling, burning, pain, tenderness, heat, anaesthesia, and hyperaesthesia. #What do you mean by systemic symptoms?# Those general symptoms, slight or profound, which are sometimes associated, primarily or secondarily, with the cutaneous disease, as, for example, the systemic disturbance in leprosy, pemphigus, and purpura hemorrhagica. #Into what two classes of lesions are the objective symptoms commonly divided?# Primary (or elementary), and Secondary (or consecutive). #Primary Lesions.# #What are primary lesions?# Those objective lesions with which cutaneous diseases begin. They may continue as such or may undergo modification, passing into the secondary or consecutive lesions. #Enumerate the primary lesions.# Macules, papules, tubercles, wheals, tumors, vesicles, blebs and pustules. #What are macules (maculae)?# Variously-sized, shaped and tinted spots and discolorations, without elevation or depression; as, for example, freckles, spots of purpura, macules of cutaneous syphilis. #What are papules (papulae)?# Small, circumscribed, solid elevations, rarely exceeding the size of a split-pea, and usually superficially seated; as, for example, the papules of eczema, of acne, and of cutaneous syphilis. #What are tubercles (tubercula)?# Circumscribed, solid elevations, commonly pea-sized and usually deep-seated; as, for example, the tubercles of syphilis, of leprosy, and of lupus. #What are wheals (pomphi)?# Variously-sized and shaped, whitish, pinkish or reddish elevations, of an evanescent character; as, for example, the lesions of urticaria, the lesions produced by the bite of a mosquito or by the sting of a nettle. #What are tumors (tumores)?# Soft or firm elevations, usually large and prominent, and having their seat in the corium and subcutaneous tissue; as, for example, sebaceous tumors, gummata, and the lesions of fibroma. #What are vesicles (vesiculae)?# Pin-head to pea-sized, circumscribed epidermal elevations, containing serous fluid; as, for example, the so-called fever-blisters, the lesions of herpes zoster, and of vesicular eczema. #What are blebs (bullae)?# Rounded or irregularly-shaped, pea to egg-sized epidermic elevations, with fluid contents; in short, they are essentially the same as vesicles and pustules except as to size; as, for example, the blebs of pemphigus, rhus poisoning, and syphilis. #What are pustules (pustulae)?# Circumscribed epidermic elevations containing pus; as, for example, the pustules of acne, of impetigo, and of sycosis. #Secondary Lesions.# #What are secondary lesions?#