But as different drugs yield their virtues with more ease, and in greater quantity to some menstrua than to others, it seemed probable, that even a very small quantity of lime might render water less solvent of particular vegetables, than it is in its pure state, though with others as large or perhaps a greater quantity than what I had used might be necessary: and as the determination of this point might be of some use in pharmacy, the following experiments were made; in the relation of which I shall make use of numbers as before, viz. the vegetable rubbed with four ounces of distilled water will be distinguished by number 1, that with two scruples of lime and four ounces of lime water, number 2, and that with lime water only, number 3. EXPERIMENT XXII. Two drachms of snake root were rubbed for fifteen minutes with the above-mentioned different proportions of distilled water, quick-lime and lime water, and lime water alone. Number 1 was a dark brown tincture, tasting strongly of the serpentaria. Number 2, straw coloured, taste of the lime disagreeable, that of the root not distinguishable. Number 3, amber coloured, tastes of the root. EXPERIMENT XXIII. Two drachms of Columbo being triturated in the same manner, Number 1, dark brown tincture; tastes much of the Columbo. Number 2, yellow; faint taste of the Columbo, but that of the lime very disagreeably prevalent. Number 3, colour as number 1; but tastes more highly of the Columbo. EXPERIMENT XXIV. Two drachms of contrayerva root with the same treatment yielded in the following proportions: Number 1 gave a pale brown tincture, tasting of the contrayerva. Number 2, bright amber colour; taste of the lime so strong as to admit of no other. Number 3 exceeded number 1 both in colour and taste. EXPERIMENT XXV. Jalap being triturated in the same proportions, Number 1 dark brown; taste of the jalap strong. Number 2 pale yellow; taste of the lime predominant, though that of the jalap perceptible. Number 3, colour not quite so high as number 1, but equal in taste. EXPERIMENT XXVI. The result of the same trial with ipecacuanha was, that number 1 was of a light brown colour, tasting highly of the ipecacuanha. Number 2 was of a deep yellow, having the same disagreeable taste of the lime complained of in the other tinctures, but that of the ipecacuanha scarcely perceptible. Number 3 produced a tincture of the colour of red port wine, strongly flavoured with the ipecacuanha, though it had not so much of the distinguishing sharpness of that root as number 1. EXPERIMENT XXVII. The different tinctures of rhubarb, prepared in the same manner as above, had the following appearances: Number 1 brown, with a yellowish tinge, strongly impregnated with the taste of the rhubarb. Number 2 deep yellow, taste of the lime as in the other tinctures prepared with it. Number 3 crimson; taste of the rhubarb strong, but unequal to number 1.