She was led to go to the south of France, to Gex, Thonon, Grenoble, Nice, Marseilles; and as she taught these things to those who came within her reach—and great numbers resorted to her—she began straightway to endure the persecutions which are promised by St. Paul to those who follow the godly life. She preached reality rather than forms. The two great principles which she clearly, strongly proclaimed were self-renunciation and perfect union with the Divine will; nothing in ourselves, but all in God. She urged also the reading and study of the Bible, which she constantly practiced herself. These things, of course, brought down upon her the severest opposition from the ruling authorities in the Church. Some were jealous of her because she was a woman; some were rebuked in their sins; some felt that she was preaching the heresies of Protestantism; some were offended at the unaccustomed terms she employed. The doctrine of full salvation by faith and complete conformity to Christ crucified, never popular in any age or land, was particularly obnoxious then and there. When persecuted in one city she fled to another, as the Savior directed, being in no haste to justify herself, leaving her vindication, for the most part, with God. She was able to do a great deal for the Master in spite of continual opposition, being occupied sometimes from six in the morning till eight at night with those who came to her for spiritual help, writing incessantly also, and scattering her productions. She established a hospital in Grenoble, and was at all times assiduous in rescuing the fallen and doing good to the needy. In one of her books written at this time, called “The Method of Prayer,” she rightly says: “No man can know whether he is wholly consecrated to the Lord except by tribulation. That is the test. To rejoice in God’s will when that will imparts nothing but happiness is easy, even for the natural man. But none but the religious man can rejoice in the Divine will when it crosses his path, disappoints his expectations, and overwhelms him with sorrow. Trial, therefore, instead of being shunned, should be welcomed as a test, and the only true test of the true state.” She nobly endured this test, not only at this time, but still more signally as the years went on. She arrived again in Paris, five years after her departure from that city, July 22, 1686. Here she became one of the little circle which met frequently for religious and social purposes at the Hotel de Beauvilliers, a circle which included Madame de Maintenon and Fénelon.